Cell migration is central to many physiological and pathological processes. It is an integral process in cancer, tissue repair and regeneration, congenital abnormalities, arthritis, tissue engineering, atherosclerosis, osteoporosis and physiological processes involved in development.
Cell migration assays use unique technology to create a detection zone to monitor cell migration. Reproducible cell migration assays are available in a wide range of different formats that can be used with Enzo’s dyes and labeling kits. Assays have been validated for a variety of cell lines including: HT-1080, PC-3, A549, NCI H1650, MDA-MB-231, NMuMG, 3T3-Swiss albino, HCEC, HUVEC, and MCF10A cell lines.
The Cell migration BioGel assays use a non-toxic biocompatible gel (BioGel) to form a cell-free detection zone on cell culture plates. After seeding cells into the plate, the BioGel dissolves permitting cells to migrate into the well centers.
The Cell Migration Assays utilize Cell Seeding Stoppers made from a medical-grade silicone to restrict cell seeding to the outer regions of the wells to create the detection zone. Removal of the stoppers reveals a 2mm diameter unseeded detection zone in the center of each well into which the seeded cells may then migrate.
| Product Name | Coating | Size | Instrument Compatibility | Detection Zone Format |
| Cell Migration BioGel Assay, TC | Tissue-Culture Treated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Automated Liquid Handler | BioGel |
| Cell Migration BioGel Assay and Invasion Assay, Collagen - I Coated | Collagen – I Coated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Automated Liquid Handler | BioGel |
| Cell Migration BioGel HT Assay, TC | Tissue-Culture Treated | 1 x 384 wells 5 x 384 wells |
High Content Imaging, Inverted Microscope, Automated Liquid Handler | BioGel |
| Cell Migration BioGel HT Assay, Collagen - I Coated | Collagen – I Coated | 1 x 384 wells 5 x 384 wells |
High Content Imaging, Inverted Microscope, Automated Liquid Handler | BioGel |
| Cell Migration Assay, TC | Tissue-Culture Treated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Microplate reader | Cell Seeding Stoppers (pre-populated) |
| Cell Migration Assay, Collagen – I Coated | Collagen – I Coated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Microplate reader | Cell Seeding Stoppers (pre-populated) |
| Cell Migration Assay, Fibronectin Coated | Fibronectin Coated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Microplate reader | Cell Seeding Stoppers (pre-populated) |
| Cell Migration Assay, Tri-Coat | Tissue-Culture Treated (32wells) Collagen – I Coated (32 wells) Fibronectin Coated (32 wells) |
1 x 96 wells | High Content Imaging, Inverted Microscope, Microplate reader | Cell Seeding Stoppers (pre-populated) |
| Cell Migration Assay, Flex Kit | Tissue-Culture Treated | 1 x 96 wells | High Content Imaging, Inverted Microscope, Microplate reader | Cell Seeding Stoppers (pre-populated) |
