Metabolism refers to a set of chemical reactions which are responsible for transforming carbohydrates, lipids and proteins into energy. These biochemical processes are essential for maintaining homeostasis. Metabolic research focuses on better understanding basic biological mechanisms that regulate metabolism and how they are dysregulated in disorders such as obesity, diabetes, cardiovascular disease, and cancer. A common root cause in these medical conditions is an energy imbalance; better understanding of this disparity will help determine therapeutic strategies. Even though metabolism involves sequences of complex biochemical reactions, Enzo Life Sciences provides simple and novel solutions to advance your metabolic research.

Browning Modulators

• Irisin (human), (recombinant) (active)
• PPAR Ligands
• Adipokines
• Adrenergic Agonists

Diabetes / Obesity Modulators

• PPAR Agonists
• PPAR Antagonist
• AMPK
• Antidiabetic Agents

Mitochondria, the organelles that generate energy for the cell, have a critical role in the function of a cell. Mitochondrial disease, stemming from dysfunction, can have various effects on the body with conditions ranging from epilepsy, psychiatric illness and autism, to cardiovascular disease, liver/kidney disease, diabetes and cancer. The impact of mitochondria in so many diseases makes them ideal targets for new therapeutics.

Mitochondria Function

MITO-ID® Membrane Potential Detection Kit for Microscopy and Flow Cytometry

The Only Assay that Monitors Energetic Status Using a Simple Mix-and-Read, No-Wash Protocol



The mitochondria of HeLa cells were stained with MITO-ID® Membrane Potential dye and visualized by epifluorescence microscope. Orange fluorescent aggregates are localized in the mitochondria, while green fluorescent monomers mainly stain the cytosol.

Mitochondria Isolation

Mitochondira/Cytosol Fraction Kit

Rapid, Ultra-sensitive Kit for the Isolation of Mitochondria and Cytosol Fractions in Two Easy Stepse Potential

• No ultracentrifugations are required
• No toxic chemicals are required
• Applications include WB, ELISA or other assays for studying apoptotic and signal transduction pathways

Mitochondria Detection

MITO-ID ® Red detection kit (GFP-CERTIFIED®)

Photostable, non-toxic and selective mitochondrial dye that stains regardless of membrane potential



HeLa-TurboGreen-mitochondria cells (HeLa-mitoGFP, MarinPharm GmbH, Luckenwalde, Germany) stained with MITO-ID® Red and Hoechst 33342 (blue) dyes. MITO-ID® Red co-localizes with the EGFP-cytochrome C oxidase signal (yellow signal), demonstrating selectivity for mitochondria. Note that mitochondria in cells no longer expressing the GFP-tagged protein appear red in the composite image.

Insulin regulates the plasma glucose level by maintaining a balance between intestinal absorption, liver production, and cellular uptake of glucose and its metabolism by peripheral tissues. Insulin triggers glucose, fatty acids, and amino acids uptake into adipose tissue, muscle, and the liver. It also promotes the storage of these nutrients in the form of glycogen, lipids, and proteins. At times of starvation, low insulin levels direct insulin-sensitive cells to mobilize stored fuels.

Enzo offers hundreds of ultrasensitive, time-saving, and widely cited ELISA kits for quantifying insulin and other metabolic biomarkers.