Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Oxidative Stress

Visualize Toxic Events In Vitro


Oxidative stress occurs when there is a disturbance in the balance between the production of reactive oxygen species (ROS) and the cell's antioxidant defenses. Exposure to drugs can induce the formation of excess ROS or lower the antioxidant defense systems of the cell. Direct drug metabolism may cause the formation of ROS or other radical species through the oxidative or reductive metabolism of the drug. Other mechanisms can disrupt essential detoxification enzymes, such as superoxide dismutase and glutathione peroxidase in mitochondria, which become overtaxed in stressing conditions. Excessive oxidant species can cause oxidative damage to mitochondrial DNA and proteins, and membrane lipids, which alter cell structure and function. Oxidative damage also aggravates mitochondrial dysfunction and creates more ROS production leading to aberrant cell bioenergetics and cell death.


TechNote

What are the different cytotoxicity assays used for in-vitro toxicology?

Download Our Predictive Toxicology Brochure


Product Highlight

ROS-ID® Hypoxia/Oxidative stress detection kit


Simultaneously monitor hypoxic status and ROS function

  • Specifically distinguishes hypoxia from oxidative stress in real-time
  • High sensitivity, specificity and accuracy for live cell studies
  • Use with adherent or suspension cell lines
  • Complete set of reagents, including ROS and hypoxia inducer controls

Specific Hypoxia Detection in HeLa cells



Hypoxia was detected in HeLa Cells (red fluorescence) treated with DFO. Oxidative stress was detected as green fluorescence.

Solutions for Oxidative Stress

Cell Counting Kit-8 

Simple, fast and accurate assay to measure cell proliferation and cytotoxicity
Colorimetric detection | Print as PDF
 
ALX-850-039-0100 100 tests 100.00 USD
 
ALX-850-039-KI01 500 tests 216.00 USD
 
ALX-850-039-KI02 5x500 tests 641.00 USD
Do you need bulk/larger quantities?
 

Cell Counting Kit-F 

Fluorescence microscopy | Print as PDF
 
ALX-850-245-KI01 500 tests 216.00 USD
 
ALX-850-245-KI02 5x500 tests 790.00 USD
Do you need bulk/larger quantities?
 

DNA damage ELISA kit 

Rapid DNA damage ELISA kit for cancer, apoptosis and oxidative stress.
ELISA, Colorimetric detection | Print as PDF
 
ADI-EKS-350 96 wells 931.00 USD
Do you need bulk/larger quantities?
 

HO-1 (human), ELISA kit 

Highly sensitive HO-1 ELISA kit enabling detection of HO-1 in cell lysates and tissue extracts in < 2.5 hours.
ELISA, Colorimetric detection | Print as PDF
 
ADI-EKS-800 96 wells 788.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Blue/Green cell viability reagent 

Distinguishes between live vs dead cells in a single reagent.
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53004-C100 100 µl 316.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Blue/Red cell viability reagent (GFP-CERTIFIED®) 

Distinguishes between live vs dead cells in a single reagent.
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53005-C100 100 µl 304.00 USD
Do you need bulk/larger quantities?
 

NUCLEAR-ID® Red/Green cell viability reagent 

Distinguishes between live vs dead cells in a single reagent
≥93% (HPLC), Flow Cytometry, Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-53006-C100 100 µl 310.00 USD
Do you need bulk/larger quantities?
 

OXI-TEK TBARS assay kit 

Fluorescent detection | Print as PDF
 
ALX-850-287-KI01 160 tests 823.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® NO Detection kit 

Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-51013-200 1 Kit 218.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® Hypoxia/Oxidative stress detection kit 

Widely cited kit for the simultaneous analysis of hypoxia and oxidative stress by microscopy and flow cytometry applications
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51042-0125 125 tests 133.00 USD
 
ENZ-51042-K500 500 tests 463.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® ROS/RNS detection kit 

Widely cited kit to measure reactive oxygen and nitrogen species in live cells by fluorescence microscopy
Fluorescence microscopy | Print as PDF
 
ENZ-51001-200 1 Kit 352.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® Superoxide detection kit 

Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51012 1 Kit 218.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® Total ROS detection kit 

Widely cited kit to measure global levels of ROS in live cells
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51011 1 Kit 214.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® Total ROS/Superoxide detection kit 

Widely cited kit to detect total ROS and Superoxide in live cells by microscopy and flow cytometry applications
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51010 1 Kit 320.00 USD
Do you need bulk/larger quantities?
 

Trouble Finding Your Predictive Toxicology Solution? Questions? Ask a Scientist Today.




Please fill the form below

We Will Contact You Within One (1) Business Day

Recommend this page