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Cardiotoxicity

Visualize Toxic Events In Vitro


Cardiotoxicity is a leading cause of safety-related drug withdrawals, which presents a need to screen for toxic events early in the drug discovery process. The most common testing done for the cardiotoxicity of drugs uses in vivo animal studies and in vitro human ether-a-go-go related gene (hERG) assay. Animal studies and hERG assays inappropriately predict cardiotoxicity in humans leading to advancements in in vitro methodologies and iPSC models. Compounds that exert cardiovascular toxicity can cause severe adverse effects such as arrhythmia, myocardium structural damage, or death. Late-stage failures can be avoided by comprehensively screening compounds to identify cardiotoxic pathways that may interfere with cardiac function or physiology.


Application Note

Multi ‐ Parameter in vitro Assessment of Compound Effects on Cardiomyocyte Physiology Using Induced Pluripotent Stem Cells (iPSC)

Download Our Predictive Toxicology Brochure


Product Highlight

Cyclic Nucleotide Analysis


We offer the most sensitive and complete colorimetric ELISA kits to quantify intracellular and/or extracellular cAMP or cGMP in various sample types.

  • Sensitive ELISA with optional acetylation protocol increases sensitivity 10-fold
  • Regularly cited in peer-reviewed publications
  • Simple, efficient, and well-established sample handling protocols with results in just 3 hours



cAMP Complete ELISA Kit – Acetylated Assay Format

Solutions for Cardiotoxicity

Angiotensin A ELISA kit 

Most sensitive Angiotensin A kit for cardiovascular research.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-207 96 wells Inquire for pricing
Do you need bulk/larger quantities?
 

Angiotensin II ELISA kit 

Highly sensitive ELISA, detecting as little as 4.6 pg/ml
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-204 96 wells 499.00 USD
Do you need bulk/larger quantities?
 

Aldosterone ELISA kit 

ELISA, Colorimetric detection | Print as PDF
 
ADI-900-173 96 wells 328.00 USD
Do you need bulk/larger quantities?
 

Bradykinin ELISA kit 

Sensitive and reliable ELISA for measuring bradykinin in plasma, serum and urine samples.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-206 96 wells 481.00 USD
Do you need bulk/larger quantities?
 

cAMP complete ELISA kit 

Most sensitive (0.037 pmol/ml) and complete colorimetric kit for intra- and extracellular cAMP quantification.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-163 96 wells 440.00 USD
Do you need bulk/larger quantities?
 

Direct cAMP ELISA kit 

Most sensitive (0.037 pmol/ml) colorimetric kit for intracellular cAMP quantification.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-066 96 wells 405.00 USD
Do you need bulk/larger quantities?
 

cAMP ELISA kit 

Most sensitive (0.039 pmol/ml) colorimetric kit for extracellular cAMP quantification.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-067 96 wells 384.00 USD
Do you need bulk/larger quantities?
 

cGMP complete ELISA kit 

Most sensitive (0.043 pmol/ml) and complete colorimetric kit for intra- and extracellular cGMP quantification.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-164 96 wells 454.00 USD
Do you need bulk/larger quantities?
 

cGMP ELISA kit 

Most sensitive (0.088 pmol/ml) colorimetric kit for extracellular cGMP quantification.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-013 96 wells 384.00 USD
Do you need bulk/larger quantities?
 

GFP-CERTIFIED® FLUOFORTE® Calcium assay kit 

A brighter, more robust and GFP-compatible (orange dye) fluorescent assay for calcium mobilization
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51020-KP010 10x96 wells 490.00 USD
 
ENZ-51020-KP100 100x96 wells 3,432.00 USD
Do you need bulk/larger quantities?
 

FLUOFORTE® Calcium assay kit  

A Brighter, More Robust Fluorescent Assay for Calcium Mobilization
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51016 100x96 tests 2,639.00 USD
Do you need bulk/larger quantities?
 

FLUOFORTE® Calcium assay kit  

A Brighter, More Robust Fluorescent Assay for Calcium Mobilization
Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51017 10x96 tests 365.00 USD
Do you need bulk/larger quantities?
 

SCREEN-WELL® Cardiotoxicity library 

Essential standards for predictive toxicology screening
HTS | Print as PDF
 
BML-2850-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2850-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

Serotonin ELISA kit 

Easy-to-use, well-validated serotonin ELISA kit for hormone research.
ELISA, Colorimetric detection | Print as PDF
 
ADI-900-175 96 wells 568.00 USD
Do you need bulk/larger quantities?
 

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