Figure 1: Proinsulin ELISA kit As a leading manufacturer of ELISAs, Enzo Life Sciences continues to grow its immunoassay portfolio for metabolic research with the introduction of the Proinsulin and Insulin ELISA kits.
Insulin is a peptide hormone made in the pancreas by beta cells and promotes the uptake of glucose from the blood into tissues, where it is stored in the form of glycogen and fat. By controlling glucose levels, insulin serves as the central regulator of fat and carbohydrate metabolism.
Proinsulin is composed of the A and B subunits of insulin and is connected by the C-peptide region. Proinsulin is processed in the endoplasmic reticulum of pancreatic b-cells and is converted within immature secretory granules into insulin and C-peptide. While mature insulin is required for glucose homeostasis and C-peptide is associated with renal function, proinsulin has low metabolic activity. The release of proinsulin is significantly increased in patients with type 2 diabetes mellitus, as well as, in individuals with impaired glucose tolerance
The Insulin and Proinsulin ELISA kits allow for the quantitative determination of insulin and proinsulin in serum and plasma. These ELISA kits provide a highly sensitive measurement, detecting as little as 0.622 µIU/mL (insulin) and 0.17 pM (proinsulin), providing fully quantitative results that surpass semi-quantitative Western blot analysis. With the ability to analyze up to 40 samples in duplicate in 3 hours, these kits meet the needs for rapid, high-throughput analysis.
Like many other Enzo Life Sciences ELISA kits, these kits are complete, flexible and thoroughly validated. Customers are supplied with a simple protocol, a pre-coated microtiter plate and liquid color-coded reagents to save time and reduce errors. The break-a-part strip plate design provides flexibility – the user does not have to run all 96-wells at once. Each kit is taken through rigorous fit-for-purpose validation and stability testing to ensure accuracy, sensitivity, and specificity.
For more information or to order the Proinsulin and Insulin ELISA kits or other Enzo Life Sciences products, please visit us at www.enzolifesciences.com or call us at 1-800-942-0430.
Enzo Life Sciences, Inc. is a wholly owned subsidiary of Enzo Biochem, Inc. headquartered in Farmingdale, New York. The company is focused on providing innovative life science research reagents worldwide based on over 30 years of successful experience in building strong international market recognition, implementing outstanding operational capabilities, and establishing a state-of-the-art electronic information and ordering marketplace.
Enzo Life Sciences, Inc. is a recognized leader in labeling and detection technologies across research and diagnostic markets. Our strong portfolio of assay kits, libraries, proteins, antibodies, peptides, and small molecules provides life science researchers tools for target identification/validation, drug discovery, cellular analysis, high content analysis, gene expression analysis, nucleic acid detection, and protein biochemistry and detection.
New Product Release
Date: August 6th 2015
For additional Information, please contact:
Kara Cannon, Global Head of Marketing
1-631-694-7070 x 145
