Replaces Prod. #: BPD-HYB-041-01
Product Specification
Alternative Name: | Pneumococcal hemolysin |
|
Clone: | 1F11 |
|
Host: | Mouse |
|
Isotype: | IgG1κ |
|
Immunogen: | S. pneumoniae. |
|
UniProt ID: | Q7ZAK5 |
|
Species reactivity: | Streptococcus pneumoniae
|
|
Applications: | ELISA, WB
|
|
Application Notes: | Detects a band of ~53kDa by Western blot. |
|
Purity Detail: | Protein A/G-affinity purified. |
|
Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
|
Shipping: | Blue Ice Not Frozen |
|
Short Term Storage: | +4°C |
|
Scientific Background: | Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae, and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes which are therefore cytotoxic to mammalian cells. The molecular weight of Pneumolysin is approximately 53kDa. |
|
Regulatory Status: | RUO - Research Use Only |
|