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Properdin (human) monoclonal antibody (10C5)

 
SSI-HYB-039-04-02 0.2 ml 545.00 USD
 
SSI-HYB-039-04-1 1 ml 2,615.00 USD
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Replaces Prod. #: BPD-HYB-039-04

Product Specification

Alternative Name:PFC, factor P
 
Clone:10C5
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Human properdin from plasma.
 
UniProt ID:P27918
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Application Notes:Detects a band of ~53kDa by Western blot.
 
Purity Detail:Protein A/G-affinity purified.
 
Formulation:Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Scientific Background:Properdin in plasma is a mixture of cyclic dimers, trimers and tetramers. The molecular weight of the glycosylated monomer is 53kDa. Properdin is a regulator protein of the alternative complement pathway. It stabilizes the C3 convertase, and binds to C3b in the C3bBb complex, thereby inhibiting cleavage of C3b by factor I and increasing the affinity for factor B.
 
Regulatory Status:RUO - Research Use Only
 

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