Alternative Name: | Apolipoprotein E3 |
|
MW: | ~34.4 kDa |
|
Source: | Produced in E. coli. Contains 301 amino acids. |
|
UniProt ID: | P02649 |
|
Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate, 0.5 mM DTT, pH 7.5. |
|
Purity: | ≥90% (SDS-PAGE) |
|
Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
|
Reconstitution: | Reconstitute in sterile 10 mM sodium phosphate, 0.5 mM DTT, pH 7.5, at 0.1 mg/mL. |
|
Shipping: | Ambient |
|
Long Term Storage: | -80°C |
|
Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
|
Scientific Background: | ApoE is a class of apolipoproteins found in the chylomicron and Intermediate-density lipoprotein (IDLs) that is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE is recognized for its importance in lipoprotein metabolism, cardiovascular disease, Alzheimer's disease (AD), immunoregulation, and cognition. |
|
Regulatory Status: | RUO - Research Use Only |
|