| Alternative Name: | Apolipoprotein E3 |
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| MW: | ~34.4 kDa |
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| Source: | Produced in E. coli. Contains 301 amino acids. |
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| UniProt ID: | P02649 |
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| Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate, 0.5 mM DTT, pH 7.5. |
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| Purity: | ≥90% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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| Reconstitution: | Reconstitute in sterile 10 mM sodium phosphate, 0.5 mM DTT, pH 7.5, at 0.1 mg/mL. |
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| Shipping: | Ambient |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | ApoE is a class of apolipoproteins found in the chylomicron and Intermediate-density lipoprotein (IDLs) that is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE is recognized for its importance in lipoprotein metabolism, cardiovascular disease, Alzheimer's disease (AD), immunoregulation, and cognition. |
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| Regulatory Status: | RUO - Research Use Only |
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