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BMPR-1A (human), (recombinant)

ENZ-PRT260-0020 20 µg 477.00 USD
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Product Specification

Alternative Name:BMP type-1A receptor, Activin receptor-like kinase 3, SKR5
MW:Dimer, 40.4/80.8 kDa (362/724 amino acids)
Source:Produced in genetically modified CHO cells. Contains a C-terminus linker (IEGRMD) and an Fc tag (Human IgG1).
UniProt ID:P36894
Formulation:Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing PBS.
Purity:>95% (SDS-PAGE)
Endotoxin Content:≤1 EU/µg
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
Long Term Storage:-80°C
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
Scientific Background:Bone morphogenetic protein receptor type-1A (BMPR-1A) is a Type I receptor that complexes with BMP Type II receptors to activate SMAD signaling. BMPR-1A is a receptor for BMP-2, BMP-4, GDF-5, and GDF-6. This product contains the first 152 amino acids of the extracellular portion of BMPR-1A and can be used to interfere with or neutralize ligand signaling.
Regulatory Status:RUO - Research Use Only
BMPR-1A (human), (recombinant) chart
Figure 1: Human BMPR1A inhibition of BMP-4 activity on ATDC5 cells
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BMPR-1A (human), (recombinant) chart

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