Alternative Name: | Interleukin-20, Cytokine Zcyto10 |
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MW: | Dimer, ~17.7/35.3 kDa |
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Source: | Produced in E. coli. Contains 153/306 amino acids. |
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UniProt ID: | Q9NYY1 |
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Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate, pH 7.5. |
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Purity: | ≥95% (SDS-PAGE) |
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Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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Shipping: | Ambient |
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Long Term Storage: | -80°C |
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Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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Scientific Background: | Interleukin 20 (IL-20) is structurally related to interleukin 10 (IL-10) and is produced by keratinocytes and monocytes. IL-20 acts through the STAT3 signaling pathway to regulate the proliferation of keratinocytes during epidermal inflammation. |
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Regulatory Status: | RUO - Research Use Only |
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