| Alternative Name: | Interleukin-5, B-cell differentiation factor I, Eosinophil differentiaion factor, TFR |
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| MW: | Dimer, ~13.1/26.3 kDa |
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| Source: | Produced in E. coli. Contains 113/226 amino acids. |
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| UniProt ID: | P04401 |
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| Formulation: | Lyophilized from a sterile (0.2 micron) filtered solution containing 20 mM sodium bicarbonate, pH 9. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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| Biological Activity: | TF-1 cell proliferation; ED50 ≤ 250 ng/mL (≥ 4.0 x 106 units/mg). |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Interleukin 5 (IL-5) is a hematopoietic growth factor that is expressed in type 2 T helper cells, mast cells, and eosinophils. IL-5 acts through the IL-5 receptor, stimulates B cell growth, and mediates eosinophil activation. |
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| Regulatory Status: | RUO - Research Use Only |
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