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FGF-6 (human), (recombinant)

 
ENZ-PRT232-0025 25 µg 276.00 USD
 
ENZ-PRT232-0100 100 µg 968.00 USD
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Product Specification

Alternative Name:Fibroblast growth factor 6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, HBGF-6
 
MW:~18.9 kDa
 
Source:Produced in E. coli. Contains 169 amino acids.
 
UniProt ID:P10767
 
Formulation:Lyophilized from a sterile (0.2 micron) filtered solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg protein (LAL test)
 
Biological Activity:3T3 proliferation with 1 µg heparin; ED50 ≤ 1 ng/mL (≥ 1.0 x 105 units/mg).
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Fibroblast growth factor 6 (FGF-6) is an important factor driving muscle differentiation and regeneration. FGF-6 is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts.
 
Regulatory Status:RUO - Research Use Only
 

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