| Alternative Name: | β-galactoside-binding lectin L-14-I, Galaptin, S-LAC lectin-I, L-14 |
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| MW: | ~14.7kDa |
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| Source: | Produced in E. coli. Monomer containing 135 aa. |
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| UniProt ID: | P09382 |
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| Formulation: | Lyophilized from a sterile filtered solution containing 10 mM sodium phosphate, pH 7.5. |
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| Purity: | ≥95% (reducing and non-reducing SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg protein measured by kinetic LAL analysis. |
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| Reconstitution: | Reconstitute in sterile water at 0.1mg/mL |
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| Shipping: | Ambient |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Galectin-1 belongs to the lectin family of carbohydrate binding proteins and binds glycans as both a monomer and a homodimer. Galectin-1 is produced in peripheral lymphoid organs and inflammatory sites. Galectin-1 plays important roles in acute and chronic inflammatory processes, cell growth, cell proliferation, and induces apoptosis of activated T cells. Galectin-1 also modulates cytokine secretion and inhibits pro-inflammatory cytokine production. |
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| Regulatory Status: | RUO - Research Use Only |
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