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United States 

Fractalkine (human), (recombinant)

 
ENZ-PRT228-0100 100 µg 636.00 USD
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Product Specification

Alternative Name:Neurotactin, CX3CL1
 
MW:~8.6kDa
 
Source:Produced in E. coli. A non-glycosylated protein containing 76 amino acids.
 
UniProt ID:P78423
 
Formulation:Lyophilized from a sterile filtered solution containing 0.1% TFA.
 
Purity:≥95% (reducing and non-reducing SDS-PAGE)
 
Endotoxin Content:≤1 EU/µg 
 
Biological Activity:The activity is determined by the dose dependent chemotaxis of human PBMCs and is typically starting between 10-100 ng/mL.
 
Reconstitution:Reconstitute in sterile water at 0.1 mg/mL.
 
Shipping:Ambient
 
Long Term Storage:-80°C
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
 
Scientific Background:Fractalkine, also known as CX3CL1, is an atypical chemokine that was the first of a fourth chemokine motif (CX3C). Fractalkine functions as a T cell and monocyte chemoattractant and is produced by non-haemopoietic cells. Fractalkine is made in a soluble and membrane bound form in activated endothelial cells which is thought to promote adhesion of leukocytes.
 
Regulatory Status:RUO - Research Use Only
 

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