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United States 

TGF-β1 (human), (recombinant)

ENZ-PRT221-0020 20 µg 841.00 USD
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Product Details

Alternative Name:Differentiation inhibiting factor, Cartilage-inducing factor, Transforming growth factor β1
MW:Dimer ~12.8/25.6 kDa
Source:Produced in CHO cells. Contains 112/224 amino acids.
UniProt ID:P01137
Formulation:Lyophilized. Contains 0.1% trifluoroacetic acid and trehalose (in a 20:1 trehalose to protein ratio).
Purity:≥95% (SDS-PAGE)
Endotoxin Content:≤1 EU/µg protein (LAL test)
Reconstitution:Reconstitute in sterile 10 mM HCl at 0.1 mg/mL.
Shipping:Ambient Temperature
Short Term Storage:+4°C
Long Term Storage:-80°C
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution.
Scientific Background:Transforming growth factor β1 (TGF-β1) is a member of the TGF-β superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-β1 signals through SMAD proteins via the TGF-βRI and TGF-βRII receptors.
Regulatory Status:RUO - Research Use Only

Product Literature References

Probing TGF-β1-induced cytoskeletal rearrangement by fluorescent-labeled silica nanoparticle uptake assay: H.R. Shin, et al.; Biochem. Biophys. Rep. 28, 101137 (2021), Abstract;

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