Product Details
| Alternative Name: | Differentiation inhibiting factor, Cartilage-inducing factor, Transforming growth factor β1 |
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| MW: | Dimer ~12.8/25.6 kDa |
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| Source: | Produced in CHO cells. Contains 112/224 amino acids. |
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| UniProt ID: | P01137 |
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| Formulation: | Lyophilized. Contains 0.1% trifluoroacetic acid and trehalose (in a 20:1 trehalose to protein ratio). |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤1 EU/µg protein (LAL test) |
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| Reconstitution: | Reconstitute in sterile 10 mM HCl at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Transforming growth factor β1 (TGF-β1) is a member of the TGF-β superfamily of cytokines. Members of this family exhibit regulatory activity in immunity, proliferation, adhesion, migration, and growth inhibition pathways. TGF-β1 signals through SMAD proteins via the TGF-βRI and TGF-βRII receptors. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Probing TGF-β1-induced cytoskeletal rearrangement by fluorescent-labeled silica nanoparticle uptake assay: H.R. Shin, et al.; Biochem. Biophys. Rep.
28, 101137 (2021),
Abstract;
