| Alternative Name: | HBBM, HARP, NEGF1, HBGF-8, Osteoblast specific factor 1, OSF-1 |
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| MW: | ~ 15.4 kDa |
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| Source: | Produced in E. coli. A non-glycosylated protein containing 137 amino acids. |
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| UniProt ID: | P21246 |
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| Formulation: | Lyophilized. Contains 10 mM sodium phosphate, pH 7.5. |
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| Purity: | ≥98% (SDS-PAGE) |
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| Endotoxin Content: | ≤0.05 EU/µg protein (LAL test) |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Pleiotrophin (Osteoblast specific factor 1, OSF-1) is a growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made predominantly in the nervous system during development and can induce neurite outgrowth. PTN has also shown a high affinity for heparin. |
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| Regulatory Status: | RUO - Research Use Only |
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