| Alternative Name: | CSF-3, G-CSF, Pluripoietin, MGI-1G |
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| MW: | ~ 18.8 kDa |
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| Source: | Produced in E. coli. A monomer containing 175 amino acids. |
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| UniProt ID: | P09919 |
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| Formulation: | Lyophilized. Contains 0.1% trifluoroacetic acid. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤ 1 EU/µg protein (LAL test) |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recommended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Granulocyte-colony stimulating factor (G-CSF) is a growth factor that induces terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by endotoxins, TNF, IL-1 and GM-CSF. IL-17 can induce synthesis in epithelial, endothelial and fibroblastic cells. Prostaglandin E2 inhibits the G-CSF. Human and mouse G-CSF are cross-reactive. |
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| Regulatory Status: | RUO - Research Use Only |
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