| Alternative Name: | SCF, c-kit ligand |
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| MW: | 35-45kDa |
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| Source: | Produced HEK293 cells. Glycosylated protein. |
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| UniProt ID: | P21583 |
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| Formulation: | Lyophilized from 1X PBS. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | <1 EU/µg |
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| Activity: | The activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells which is typically observed at ≤25 ng/mL. |
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| Reconstitution: | Reconstitute in sterile 1X PBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA). |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Handling: | Centrifuge the vial before opening the cap. After reconstitution, prepare aliquots and store at -20°C. |
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| Scientific Background: | SCF is produced in a human cell expression system with serum-free, chemically defined media. Production in HEK293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications. SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation, and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. |
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| Regulatory Status: | RUO - Research Use Only |
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