| Alternative Name: | BMP-2 |
| |
| MW: | 30-38kDa |
| |
| Source: | Produced in HEK cells. Glycosylated disulfide-linked homodimer. |
| |
| UniProt ID: | P12643 |
| |
| Formulation: | Lyophilized from 1 mg/mL in 1X PBS. |
| |
| Purity: | ≥95% (SDS-PAGE) |
| |
| Purity Detail: | Sterile filtered. |
| |
| Appearance: | White powder. |
| |
| Specific Activity: | The specific activity was ≤60ng/mL as determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line. |
| |
| Reconstitution: | Reconstitute with sterile 4 mM HCl containing 0.1% endotoxin-free recombinant HSA. |
| |
| Shipping: | Ambient Temperature |
| |
| Short Term Storage: | +4°C |
| |
| Long Term Storage: | -20°C |
| |
| Use/Stability: | The reconstituted solution can be stored at +4°C for 1 week. |
| |
| Handling: | After reconstitution, prepare aliquots and store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% BSA or serum). |
| |
| Scientific Background: | BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily or structurally related signaling proteins. Bone morphogenic protein induces bone and cartilage formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
