| ENZ-PRT169-0010 | 10 µg | 399.00 USD |  |
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| Do you need bulk/larger quantities? | |||||
| Alternative Name: | CTSL1, MEP, CATL, CTSL |
| MW: | ~36.7 kDa |
| Source: | Produced in HEK 293 cells. |
| EC: | 3.4.22.15 |
| UniProt ID: | P07711 |
| Formulation: | Lyophilized from 0.22µm filtered solution in 50mM sodium acetate, pH 5.0, containing 100mM NaCl. Generally 5-8% mannitol or trehalose is added as a protectant before lyophilization. |
| Purity: | ≥98% (SDS-PAGE) |
| Shipping: | Blue Ice |
| Short Term Storage: | -20°C |
| Long Term Storage: | -20°C |
| Scientific Background: | Cathepsin L1 plays an important role in the overall degradation of proteins in lysosomes. Its substrates include collagen and elastin, as well as α-1 protease inhibitor, a major controlling element of neutrophil elastase activity. It has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. |
| Regulatory Status: | RUO - Research Use Only |
