Alternative Name: | CA4, Carbonic anhydrase IV, CA-IV |
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MW: | ~31 kDa |
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Source: | Produced in HEK 293 cells. |
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EC: | 4.2.1.1 |
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UniProt ID: | P22748 |
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Formulation: | Lyophilized from 0.22µm filtered solution in 50mM TRIS, pH 7.5, containing 150mM NaCl. Normally mannitol or trehalose is added as protectant before lyophilization. |
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Purity: | ≥92% (SDS-PAGE) |
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Shipping: | Blue Ice |
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Short Term Storage: | -20°C |
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Long Term Storage: | -20°C |
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Scientific Background: | Carbonic anhydrase 4 catalyzes the reversible hydration of carbon dioxide. It may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid. |
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Regulatory Status: | RUO - Research Use Only |
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