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Epidermal growth factor (human), (recombinant)

ENZ-PRT154-0010 10 µg 301.00 USD
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Product Details

Alternative Name:EGF, URG, HOMG4
MW:~6.3 kDa
Source:Produced in HEK 293 cells.
UniProt ID:P01133
Formulation:Lyophilized from 0.22 µm filtered PBS (pH 7.4) with 5% trehalose.
Purity:≥95% (SDS-PAGE)
Applications:ELISA, WB
in vitro Assay
Application Notes:Western Blot (control)
Reconstitution:Reconstitute in sterile PBS, pH 7.4 up to 0.2 µg/µl.
Shipping:Blue Ice
Short Term Storage:-20°C
Long Term Storage:-20°C
Use/Stability:The reconstituted solution can be stored at 2-8°C for up to 1 month. For long term storage, store at -20 °C.
Handling:Centrifuge vial prior to opening. Do not vortex.
Scientific Background:Human epidermal growth factor (EGF, also known as beta-urogastrone) is a 53 amino acid peptide that regulates cell growth, proliferation, and differentiation. EGF is an integral membrane protein that is cleaved and released into the extracellular space where it acts as a hormone. EGF binds cell surface EGF receptors (EGFR), initiating signaling cascades through activation of EGFR tyrosine kinase activity.
Regulatory Status:RUO - Research Use Only

Product Literature References

Endothelin A (ETA) and Endothelin B (ETB) Receptor Subtypes Potentiate Epidermal Growth Factor (EGF)-Mediated Proliferation in Human Asthmatic Bronchial Airway Smooth Muscle: M.A. Almikhlafi, et al.; Cureus 14, e28333 (2022), Abstract;

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