Product Details
| Alternative Name: | EGF, URG, HOMG4 |
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| MW: | ~6.3 kDa |
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| Source: | Produced in HEK 293 cells. |
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| UniProt ID: | P01133 |
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| Formulation: | Lyophilized from 0.22 µm filtered PBS (pH 7.4) with 5% trehalose. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Applications: | ELISA, WB
in vitro Assay
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| Application Notes: | Western Blot (control) |
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| Reconstitution: | Reconstitute in sterile PBS, pH 7.4 up to 0.2 µg/µl. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -20°C |
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| Use/Stability: | The reconstituted solution can be stored at 2-8°C for up to 1 month. For long term storage, store at -20 °C. |
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| Handling: | Centrifuge vial prior to opening. Do not vortex. |
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| Scientific Background: | Human epidermal growth factor (EGF, also known as beta-urogastrone) is a 53 amino acid peptide that regulates cell growth, proliferation, and differentiation. EGF is an integral membrane protein that is cleaved and released into the extracellular space where it acts as a hormone. EGF binds cell surface EGF receptors (EGFR), initiating signaling cascades through activation of EGFR tyrosine kinase activity. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Endothelin A (ETA) and Endothelin B (ETB) Receptor Subtypes Potentiate Epidermal Growth Factor (EGF)-Mediated Proliferation in Human Asthmatic Bronchial Airway Smooth Muscle: M.A. Almikhlafi, et al.; Cureus
14, e28333 (2022),
Abstract;
