| Alternative Name: | Rspo-1, Roof plate-specific spondin-1 |
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| MW: | ~40 kDa |
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| Source: | Produced in CHO cells. |
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| UniProt ID: | Q2MKA7 |
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| Formulation: | Lyophilized from 10mM sodium phosphate, pH 7.5, containing 150mM NaCl. |
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| Purity: | ≥95% (SDS-PAGE gel & HPLC) |
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| Shipping: | Ambient |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/β-catenin signaling pathway. |
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| Regulatory Status: | RUO - Research Use Only |
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