Product Details
| Alternative Name: | Bone morphogenetic protein 4 |
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| Source: | Produced in E.coli. |
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| UniProt ID: | P12644 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥98% (SDS-PAGE gel & HPLC) |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-β superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2: X. Guo, et al.; Nat. Commun.
13, 7907 (2022),
Abstract;
