Alternative Name: | Glial cell-derived neurotrophic factor, Astrocyte-derived trophic factor, ATF |
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Source: | Produced in E.coli. |
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UniProt ID: | P39905 |
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Formulation: | Lyophilized from 10 mM sodium citrate, containing 150mM NaCl. |
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Purity: | ≥98% (SDS-PAGE gel & HPLC) |
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Shipping: | Ambient |
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Short Term Storage: | -20°C |
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Long Term Storage: | -20°C |
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Scientific Background: | GDNF is a small protein that potently promotes the survival of many types of neurons. The most prominent feature of GDNF is its ability to support the survival of dopaminergic and motorneurons. These neuronal populations die in the course of Parkinson's disease and amyotrophic lateral sclerosis (ALS). GDNF also regulates kidney development and spermatogenesis, and it affects alcohol consumption.
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Regulatory Status: | RUO - Research Use Only |
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