| Alternative Name: | Melanoma-derived growth regulatory protein, Melanoma inhibitory activity protein |
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| MW: | ~12.2 kDa |
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| Source: | Produced in E.coli. |
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| UniProt ID: | Q16674 |
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| Formulation: | Lyophilized from 15mM sodium phosphate, pH 7.2, containing 75mM NaCl. |
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| Purity: | ≥98% (SDS-PAGE gel & HPLC) |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis. |
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| Regulatory Status: | RUO - Research Use Only |
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