Product Details
Alternative Name: | Interleukin-4 |
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MW: | ~14 kDa |
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Source: | Produced in E.coli. |
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UniProt ID: | P07750 |
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Formulation: | Lyophilized. |
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Purity: | ≥98% (SDS-PAGE gel & HPLC) |
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Shipping: | Ambient Temperature |
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Short Term Storage: | -20°C |
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Long Term Storage: | -20°C |
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Scientific Background: | Interleukin 4 is a cytokine that has various biological functions including stimulation of activated B-cells, stimulation of T-cell proliferation, and the differentiation of B cells into plasma cells. It is a key regulator in humoral and adaptive immunity. IL-4 decreases the production of Th1 cells, macrophages, IFN-γ, and dendritic cell IL-12. Overexpression of IL-4 is associated with allergies.
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Deacetylasperulosidic Acid Ameliorates Pruritus, Immune Imbalance, and Skin Barrier Dysfunction in 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis NC/Nga Mice: J.-S. Oh, et al.; Int. J. Mol. Sci.
23, 226 (2022),
Abstract;