Alternative Name: | O6-Methylguanine-DNA methyltransferase |
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MW: | 25kDa |
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Source: | Produced in E. coli. |
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EC: | 2.1.1.63 |
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UniProt ID: | P16455 |
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Formulation: | Liquid. In 20mM TRIS, pH 7.5, containing 1mM DTT, 1mM EDTA, 200mM NaCl and 50% glycerol. |
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Purity: | ≥90% |
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Specific Activity: | ≥10,000 Units/mg. One unit is defined as the amount of protein that cleaves 50% of 0.5 pmole of dsDNA oligomer substrate (O6-methylguanine) in 10 min at 37°C. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Use/Stability: | Aliquots are stable for at least 6 months at -20°C. |
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Handling: | Do not store at -80°C. |
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Scientific Background: | MGMT levels serves as an indicator of DNA damage. |
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Regulatory Status: | RUO - Research Use Only |
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