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NGAL (mouse), (recombinant)

 
ENZ-PRT114-1000 1 ml 376.00 USD
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Product Details

Alternative Name:Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Oncogene 24p3
 
Source:Produced in E. coli.
 
UniProt ID:P11672
 
Concentration:1000pg/ml
 
Formulation:Liquid. In 0.01 M phosphate buffer, pH 7.4, containing 0.14 M NaCl, 0.5% BSA, 0.5% Tween 20, 0.0016% Phenol red, and 0.1% Proclin 950.
 
Applications:ELISA
 
Shipping:Blue Ice Not Frozen
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Scientific Background:Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.
 
Regulatory Status:RUO - Research Use Only
 

General Literature References

Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury: Mishra, et al.; J. Am. Soc. Nephrol. 14, 2534 (2003),
High expression in involuting reproductive tissues of uterocalin/24p3, a lipocalin and acute phase protein: Ryon, et al.; Biochem. J. 367, 271 (2002),
Identification of a new acute phase protein: Liu, et al.; J. Biol. Chem. 270, 22565 (1995),
Mouse oncogene protein 24p3 is a member of the lipocalin protein family: Flower, et al.; Biochem. Biophys. Res. Commun. 180, 69 (1991),
SV40-induced expression of mouse gene 24p3 involves a posttranscriptional mechanism: Hraba-Renevey, et al.; Oncogene 4, 601 (1989),

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