Fluoxetine metabolite that induces long QT syndrome via slow delayed rectifier potassium current block. It is a time-dependent inhibitor of CYP2C19 and CYP3A4. The active N-demethylated metabolite is a potent and selective inhibitor of serotonin uptake in vivo. Also inhibits coxsackievirus replication acting via inhibition of viral RNA synthesis. State-dependent TREK-2 blocker.
Product Details
| Alternative Name: | Desmethylfluoxetine |
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| Formula: | C16H16F3NO HCl |
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| MW: | 331.8 |
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| CAS: | 57226-68-3 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Identity determined by NMR. |
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| Appearance: | Beige waxy solid. |
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| Solubility: | Soluble in DMSO (25 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 year after receipt when stored unopened at -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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