dBET6 is chemical degrader of BET bromodomain proteins based on PROTAC and led a collapse of global elongation that phenocopies CDK9 inhibition.
Product Details
| Formula: | C42H45ClN8O7S |
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| MW: | 841.4 |
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| CAS: | 1950634-92-0 |
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| Purity: | ≥98% (LCMS) |
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| Appearance: | White to light yellow solid. |
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| Solubility: | Soluble in DMSO (240 mg/mL). Insoluble in water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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General Literature References
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment: G.E. Winter, at al.; Mol. Cell
67, 5 (2017),
Abstract;
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