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United States 

Brivanib alaninate

Inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, FGFR-1, FGFR-2, and FGFR-3
ENZ-CHM181-0005 5 mg 172.00 USD
ENZ-CHM181-0010 10 mg 279.00 USD
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Brivanib inhibits VEGFR -2 with an IC50 of 25 nmol/l and a Ki of 26 nmol/l, VEGFR-1 with an IC50 of 380 nmol/l and VEGFR-3 with an IC50 of 10 nmol/l. It also shows selectivity for FGFR-1 with an IC50 of 148 nmol/l, FGFR-2 with an IC50 of 25nmol/l and FGFR-3 with an IC50 of 68 nmol/l.

Product Details

Purity:≥97% (HPLC)
Identity:Determined by EM-MS, NMR
Appearance:Yellow powder.
Solubility:Soluble in DMSO (74mg/ml) or ethanol (3mg/ml).
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
ENZ-CHM181 structure
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ENZ-CHM181 structure