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Inhibitor of VEGFR-2
ENZ-CHM180-0005 5 mg 196.00 USD
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BMS-540215 is an ATP-competitive inhibitor of human VEGFR-2, with an IC50 of 25 nM and Ki of 26 nmol/l. BMS-540215 also showed good selectivity for FGFR-1 (IC50 of 48 nM), FGFR-2 (IC50 of 125 nM), and FGFR-3 (IC50 of 68 nM).

Product Details

Alternative Name:BMS-540215, (2R)-1-[4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]propanol
Purity:≥98% (HPLC)
Identity:Determined by EM-MS, NMR
Appearance:Yellow powder.
Solubility:Soluble in DMSO (74mg/ml) or ethanol (3mg/ml)
Shipping:Ambient Temperature
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
ENZ-CHM180 structure
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ENZ-CHM180 structure