Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

PD173955

Dual Src/Abl kinase inhibitor
 
ENZ-CHM170-0001 1 mg 195.00 USD
 
ENZ-CHM170-0005 5 mg 334.00 USD
Do you need bulk/larger quantities?
 
PD173955 is an ATP-competitive, dual Src/Abl kinase inhibitor. It is a potent inhibitor of Bcr-Abl with an IC50 of 1-2 nM in kinase inhibition assays. In cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 also inhibits Src kinase activity in vitro with an IC50 of 22 nM and could represent a novel class of anti-mitotic drug.

Product Details

Alternative Name:6-(2,6-dichlorophenyl)-8-methyl-2-(3-methylsulfanylanilino)pyrido[2,3-d]pyrimidin-7-one
 
Formula:C21H16Cl2N4OS
 
MW:443.4
 
CAS:260415-63-2
 
Purity:≥98% (HPLC)
 
Identity:Determined by EM-MS, NMR
 
Appearance:White powder.
 
Solubility:Soluble in DMSO (112mg/ml) or ethanol (4mg/ml).
 
Shipping:Ambient
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Regulatory Status:RUO - Research Use Only
 
ENZ-CHM170 structure
Please mouse over
ENZ-CHM170 structure

Product Toolbox

PRODUCT RESOURCES

Datasheet
SDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Src kinase
Abl
By biological activity:
Src kinase Inhibitor
Abl Inhibitor
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

All new literature pieces