NVP-BKM120 is a potent, selective, orally bioavailable Class I PI3Kα Inhibitor with IC50 of 20nM, currently in phase II clinical trials for the treatment of cancer. It exhibits lower potency against class III and class IV PI3Ks.
Product Details
| Alternative Name: | Buparlisib, NVP-BKM120 |
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| Formula: | C18H21F3N6O2 |
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| MW: | 410.4 |
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| CAS: | 944396-07-0 |
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| Purity: | ≥97% (HPLC) |
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| Identity: | Determined by EM-MS, NMR |
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| Appearance: | White powder. |
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| Solubility: | Soluble in DMSO (44mg/ml) or ethanol (<1mg/ml). |
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| Shipping: | Ambient |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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