NVP-BKM120 is a potent, selective, orally bioavailable Class I PI3Kα Inhibitor with IC50 of 20nM, currently in phase II clinical trials for the treatment of cancer. It exhibits lower potency against class III and class IV PI3Ks.
Product Specification
Alternative Name: | Buparlisib, NVP-BKM120 |
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Formula: | C18H21F3N6O2 |
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MW: | 410.4 |
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CAS: | 944396-07-0 |
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Purity: | ≥97% (HPLC) |
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Identity: | Determined by EM-MS, NMR |
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Appearance: | White powder. |
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Solubility: | Soluble in DMSO (44mg/ml) or ethanol (<1mg/ml). |
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Shipping: | Ambient |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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