KU55933 is a potent and selective ATP-competitive inhibitor of ATM, with an IC50 of 13 nmol/l and a Ki of 2.2 nmol/l. KU55933 has potential for use as a new radio- and chemo-sensitizing agent for the treatment of cancer.
Product Details
| Alternative Name: | ATM kinase inhibitor, 2-Morpholino-6-(thianthren-1-yl)-4H-pyran-4-one |
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| Formula: | C21H17NO3S2 |
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| MW: | 395.5 |
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| CAS: | 587871-26-9 |
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| Purity: | ≥99% (HPLC) |
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| Identity: | Determined by EM-MS, NMR |
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| Appearance: | Beige powder. |
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| Solubility: | Soluble in DMSO (50 mg/ml) or ethanol (<13 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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