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United States 

mTOR inhibitor WYE-132

Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
ENZ-CHM140-0001 1 mg 108.00 USD
ENZ-CHM140-0005 5 mg 340.00 USD
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A highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Shows an anti-proliferative activity against a variety of tumor cell lines. WYE-132 causes inhibition of protein synthesis and cell size, induction of apoptosis, and cell cycle progression.

Product Details

Alternative Name: 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132
Purity:≥99% (HPLC)
Appearance:White powder solid.
Solubility:Soluble in DMSO.
Shipping:Ambient Temperature
Short Term Storage:-20°C
Long Term Storage:-80°C
Regulatory Status:RUO - Research Use Only
ENZ-CHM140 structure
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ENZ-CHM140 structure