A highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Shows an anti-proliferative activity against a variety of tumor cell lines. WYE-132 causes inhibition of protein synthesis and cell size, induction of apoptosis, and cell cycle progression.
Product Details
| Alternative Name: | 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132 |
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| Formula: | C27H33N7O4 |
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| MW: | 519.6 |
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| CAS: | 1144068-46-1 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White powder solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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