Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian target of rapamycin) inhibitor (IC50 = 0.08 nM). WYE-28 displays 75-fold selectivity over PI3Kα (IC50 = 6 nM).
Product Details
| Alternative Name: | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
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| Formula: | C30H34N8O5 |
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| MW: | 586.6 |
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| CAS: | 1062172-60-4 |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | White powder solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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