Inhibitor of the active site of mTOR kinase in both mTORC1 and mTORC2. pp242 has been shown to cause the death of certain human and murine leukemia cells more potently than rapamycin.
Product Details
| Alternative Name: | PP-242, 2-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol, 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol |
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| Formula: | C16H16N6O . H2O |
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| MW: | 326.3 |
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| CAS: | 1092351-67-1 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White powder solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | -20°C |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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