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Akt inhibitor VIII

Potent inhibitor of Akt1, Akt2 and Akt3 activity.
 
ENZ-CHM125-0001 1 mg 111.00 USD
 
ENZ-CHM125-0005 5 mg 186.00 USD
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A cell-permeable compound that potently, selectively and reversibly inhibits Akt1/Akt2/Akt3 activity.

Product Details

Alternative Name:Akti-1/2, Isozyme-selective Akt inhibitor VIII, 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Imidazoquinoxaline 16h
 
Formula:C34H29N7O
 
MW:551.6
 
CAS:612847-09-3
 
Purity:≥98% (HPLC)
 
Appearance:Yellow powder solid.
 
Solubility:Soluble in DMSO or methanol.
 
Shipping:Ambient
 
Short Term Storage:-20°C
 
Long Term Storage:-80°C
 
Regulatory Status:RUO - Research Use Only
 
ENZ-CHM125 structure
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ENZ-CHM125 structure

Product Literature References

Carboxyl group-modified α-lactalbumin induces TNF-α-mediated apoptosis in leukemia and breast cancer cells through the NOX4/p38 MAPK/PP2A axis: J.T. Chiou, et al.; Int. J. Biol. Macromol. 187, 513 (2021), Abstract;
Comparative Analysis of CTRP-Mediated Effects on Cardiomyocyte Glucose Metabolism: Cross Talk between AMPK and Akt Signaling Pathway: L. Li, et al.; Cells 10, 905 (2021), Abstract;

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