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Akt inhibitor VIII

Potent inhibitor of Akt1, Akt2 and Akt3 activity.



ENZ-CHM125-0001	1 mg	111.00 USD

ENZ-CHM125-0005	5 mg	186.00 USD
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A cell-permeable compound that potently, selectively and reversibly inhibits Akt1/Akt2/Akt3 activity.

Product Details

Alternative Name:	Akti-1/2, Isozyme-selective Akt inhibitor VIII, 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Imidazoquinoxaline 16h

Formula:	C₃₄H₂₉N₇O

MW:	551.6

CAS:	612847-09-3

Purity:	≥98% (HPLC)

Appearance:	Yellow powder solid.

Solubility:	Soluble in DMSO or methanol.

Shipping:	Ambient

Short Term Storage:	-20°C

Long Term Storage:	-80°C

Regulatory Status:	RUO - Research Use Only

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Product Literature References

Carboxyl group-modified α-lactalbumin induces TNF-α-mediated apoptosis in leukemia and breast cancer cells through the NOX4/p38 MAPK/PP2A axis: J.T. Chiou, et al.; Int. J. Biol. Macromol. 187, 513 (2021), Abstract;

Comparative Analysis of CTRP-Mediated Effects on Cardiomyocyte Glucose Metabolism: Cross Talk between AMPK and Akt Signaling Pathway: L. Li, et al.; Cells 10, 905 (2021), Abstract;