| Alternative Name: | Myoblast determination protein 1, Myogenic factor 3 |
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| Clone: | rMYD712 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Recombinant human MyoD1. |
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| UniProt ID: | P15172 |
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| Species reactivity: | Human
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| Specificity: | Recognizes a phospho-protein of 45kDa, identified as MyoD1. |
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| Crossreactivity: | Does not cross react with myogenin, Myf5, or Myf6. |
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| Applications: | IHC
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| Application Notes: | Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. |
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| Purity Detail: | Protein G affinity purified. |
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| Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas. |
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| Regulatory Status: | RUO - Research Use Only |
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