| Alternative Name: | Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit α-1, CBF-α-1, Osteoblast-specific transcription factor 2, OSF-2 |
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| Host: | Rabbit |
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| Isotype: | IgG |
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| Immunogen: | Recombinant protein fragment from the internal region of human RUNX2. |
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| UniProt ID: | Q13950 |
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| Species reactivity: | Human, Mouse
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| Applications: | WB
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| Purity Detail: | Protein A affinity purified. |
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| Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | RUNX (runt-related transcription factor) proteins are a family of transcription factors involved in many different biological systems, including cell differentiation and cancer. RUNX2 is an essential factor in bone development, acting as a scaffold protein for nucleic acids and regulatory factors involved in skeletal gene expression. It is also involved in cancer cell movement, activating factors involved in the metastasis of prostate and breast cancer cells to bone. |
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| Regulatory Status: | RUO - Research Use Only |
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