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IKK β monoclonal antibody (IKB355)

 
ENZ-ABS767-0100 100 µg 425.00 USD
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Product Specification

Alternative Name:Inhibitor of nuclear factor κ-B kinase subunit beta, IκB kinase β, IKK2, NF-κB inhibitor kinase β
 
Clone:IKB355
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant protein fragment of IKK β.
 
UniProt ID:O14920
 
Species reactivity:Human, Mouse
 
Applications:WB
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:NF-κB is sequestered in the cytoplasm by IκBα, unable to translocate to the nucleus. IκB is part of the canonical pathway for NF-κB activation. IKKβ is part of the IκB kinase complex, along with a second catalytic subunit, IKKα, and a regulatory subunit, IKKγ. Along with IKKα, IKKβ phosphorylates IκBα leading to its degradation and release of inhibition of NF-κB. The RELA subunit of active NF-κB is then free to enter the nucleus and initiate a number of signaling cascades.
 
Regulatory Status:RUO - Research Use Only
 
IKK beta monoclonal antibody (IKB355) WB
Western blot testing of human samples with IKK β antibody IKB355 at 2µg/ml.
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IKK beta monoclonal antibody (IKB355) WB

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