Alternative Name: | Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor |
|
Host: | Rabbit |
|
Isotype: | IgG |
|
Immunogen: | Recombinant protein fragment from N-terminal human KLF4. |
|
UniProt ID: | O43474 |
|
Species reactivity: | Human, Mouse, Rat
|
|
Applications: | WB
|
|
Purity Detail: | Protein A affinity purified. |
|
Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Blue Ice |
|
Long Term Storage: | -20°C |
|
Scientific Background: | Krueppel-like factor family members are involved in growth regulation and a wide range of developmental processes. KLF4 is highly expressed in epithelial tissues including skin and stomach/intestine. Studies have shown that KLF4 can function as both an oncogene, upregulating hSSC, and a tumor suppressor, down-regulating colorectal cancer. KLF4 is involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. |
|
Regulatory Status: | RUO - Research Use Only |
|