Alternative Name: | Aldo-keto reductase 1B1, Aldehyde reductase |
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Clone: | ARD1-1 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant protein was used as the immunogen for this AKR1B1 antibody. |
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UniProt ID: | P15121 |
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Species reactivity: | Human
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Applications: | IHC, WB
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Recommended Dilutions/Conditions: | Western Blot (0.5-1 µg/ml) IHC (0.5-1 µg/ml for 30 min at RT) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein G affinity purified |
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Formulation: | Liquid. In 1X PBS containing 0.1 mg/ml BSA and 0.05% sodium azide. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The AKR1B1 gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. |
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Regulatory Status: | RUO - Research Use Only |
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