Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10)

 
ENZ-ABS759-0100 100 µl 390.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:AKR1C1, AK1C1
 
Clone:AT6D10
 
Host:Mouse
 
Isotype:IgG1κ
 
Immunogen:Recombinant human AKR1C1 (aa 1-323) purified from E. coli.
 
UniProt ID:Q04828
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry, ICC, IF, WB
 
Purity Detail:Protein G affinity purified
 
Formulation:Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-androstanediol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstanediol, respectively.
 
Regulatory Status:RUO - Research Use Only
 
Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) SDS-PAGE
The Recombinant protein (50ng) and Cell lysates (40µg) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human AKR1C1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1: Recombinant Human AKR1C1, Lane 2: HepG2 cell lysate, Lane 3: Raji cell lysate.
Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) FACS
Flow cytometry analysis of AKR1C1 in A431 cell line, staining at 2-5ug for 1x106 cells (red line). The secondary antibody used goat anti-mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was mouse IgG (black line).
Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) IF
IF analysis of AKR1C1 in A431 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AKR1C1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
Please mouse over
Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) SDS-PAGE Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) FACS Aldo-keto Reductase 1C1 monoclonal antibody (AT6D10) IF

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Aldo-keto reductase
By biological activity:
Aldo-keto reductase Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
Keep in touch

©2020 Enzo Life Sciences, Inc.,