| Alternative Name: | PFKM, PFK-1 |
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| Clone: | AT2F11 |
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| Host: | Mouse |
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| Isotype: | IgG2aκ |
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| Immunogen: | Recombinant human PFKM (aa 1-780) purified from E. coli. |
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| UniProt ID: | P08237 |
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| Species reactivity: | Human
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| Applications: | ELISA, WB
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| Purity Detail: | Protein A affinity purified |
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| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | PFKM (phosphofructokinase, muscle) is a regulatory glycolytic enzyme that convert fructose 6-phosphate and ATP into fructose 1, 6-bisphosphate (through PFK-1), fructose 2, 6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. |
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| Regulatory Status: | RUO - Research Use Only |
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