| ENZ-ABS757-0100 | 100 µl | 464.00 USD |  |
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| Alternative Name: | HK3, Hexokinase type III, Hexokinase-C |
| Clone: | AT4C12 |
| Host: | Mouse |
| Isotype: | IgG1κ |
| Immunogen: | Recombinant human Hexokinase 3 (aa 1-923) purified from E. coli. |
| UniProt ID: | P52790 |
| Species reactivity: | Human |
| Applications: | ELISA, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:2,000). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein A affinity purified |
| Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
| Handling: | Avoid freeze/thaw cycles. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes - types 1 to 4 hexokinases - have been identified. The enzyme is found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase 3 may have anabolic functions, providing H6P for glycogen or lipid synthesis. |
| Regulatory Status: | RUO - Research Use Only |
