Alternative Name: | Programmed cell death 4 isoform 1, Neoplastic transformation inhibitor protein |
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Clone: | k4C1 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant human PDCD4 (aa 1-469) purified from E. coli. |
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UniProt ID: | Q53EL6 |
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Source: | Purified from ascites. |
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Purity Detail: | Protein G affinity purified |
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Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Programmed cell death 4 (PDCD4) encodes a tumor suppressor protein whose expression is lost in progressed carcinomas of lung, breast, colon, and prostate. The expression of PDCD4 gene is strongly induced during apoptosis in a number of cell types. It is modulated by cytokines in natural killer and T cells. |
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Regulatory Status: | RUO - Research Use Only |
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