Alternative Name: | Macrophage migration inhibitory factor, GLIF, Glycosylation-inhibiting factor |
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Clone: | 4E5 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Recombinant human MIF (aa 1-114) purified from E. coli. |
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UniProt ID: | P14174 |
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Source: | Purified from ascites. |
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Species reactivity: | Human
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Applications: | ELISA, ICC, IF, WB
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Recommended Dilutions/Conditions: | Western Blot (1:1,000). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Protein G affinity purified |
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Formulation: | Liquid. In PBS, pH 7.4, containing 0.02% sodium azide and 10% glycerol. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. |
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Regulatory Status: | RUO - Research Use Only |
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